Do Environmental Factors Modify the Genetic Risk of Prostate Cancer?
نویسندگان
چکیده
From the Department of Urology and Population Health, New York University, New York, NY, the Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, the Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, the Brady Urological Institute and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Medical Institutions, Baltimore, MD
منابع مشابه
Re: Do environmental factors modify the genetic risk of prostate cancer?
BACKGROUND Many SNPs influence prostate cancer risk. To what extent genetic risk can be reduced by environmental factors is unknown. METHODS We evaluated effect modification by environmental factors of the association between susceptibility SNPs and prostate cancer in 1,230 incident prostate cancer cases and 1,361 controls, all white and similar ages, nested in the Prostate, Lung, Colorectal,...
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The prostate is a small gland located below the bladder and upper part of the urethra. In developed countries prostate cancer is the second common cancer (after skin cancer), and also the second leading cause of cancer death (after lung cancer) among men. The several studies have been shown prostate cancer familial aggregation. The main reason for this aggregation is inheritance included genes....
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